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71.
Derenko M. V. Denisova G. A. Malyarchuk B. A. Dambueva I. K. Luzina F. A. Lotosh E. A. Dorzhu Ch. M. Karamchakova O. N. Solovenchuk L. L. Zakharov I. A. 《Russian Journal of Genetics》2001,37(10):1177-1184
Using the data on mitochondrial DNA (mtDNA) polymorphism, genetic structures of the four Turkic-speaking ethnic groups of Altai–Sayan highlands, Southern Altaians (Altai- Kizhi), Khakassians, Shorians, and Sojots, were described. Mitochondrial gene pools of the populations examined were characterized by different ratios between Mongoloid (M*, C, D, E, G, A, B, and F) and Caucasoid (H, U, T, J, and K) mtDNA lineages. All the populations studied had a strongly pronounced Mongoloid component, the frequency of which was 88.2% in Sojots, 75.9% in Khakassians, 67.4% in Altaians, and 64.3% in Shorians. Maximum frequency of the Caucasoid component (35.7%) was observed in Shorians. Phylogenetic and statistical analyses of the mtDNA group frequency distribution patterns in the gene pools of the ethnic populations of Altai–Sayan highlands and the adjacent territories showed that the populations of the region fell into three groups. The first group included Khakassians, Tuvinians and Altaians, the second group consisted of Sojots, Buryats, and Mongols, while the third group was composed of Uigurs, Kazakhs, and Kyrgyzes. The isolated position of Shorians among the populations examined can be explained by their different anthropological composition and their presumptive relatedness to Finno-Ugric populations of Siberia. 相似文献
72.
Selikhovkin A. V. Baryshnikova S. V. Denisova N. V. Timofeeva Yu. A. 《Entomological Review》2018,98(8):963-978
Entomological Review - The paper summarizes new and literature data on the species composition, trophic relationships, and population dynamics of phyllophagous lepidopterans dominant on woody... 相似文献
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Mária Chrenková A. Sommer Zuzana Čerešňáková Soňa Nitrayová Miroslava Prostredná 《Archives of animal nutrition》2013,67(3):229-235
The aim of this study was to determine the composition and nutritional value of conventional and transgenic, so-called Roundup Ready (RR) maize with an introduced gene of glyphosate resistance. Crude protein, crude fibre, ash, fat, starch, sugar, amino acids, fatty acid and macroelement levels were determined by chemical analysis. In both maize lines a low level of Ca (0.15g.kg m 1 DM) and of the essential amino acids lysine and tryptophan (2.6 and 1.7g.kgm 1 DM, respectively) were observed. In the biological experiment carried out on rats the tested maize lines were the only dietary sources of nitrogen, thus, the experimental diets contained 9% CP in dietary dry matter. In the feeding experiment no significant differences in the protein efficiency ratio (PER) were observed between groups receiving conventional or transgenic maize (1.51 and 1.41, respectively). Also almost equal results were obtained in the balance experiments. Both maize lines revealed a high nitrogen digestibility (84.9 and 84.5%, respectively) and the net protein utilization amounted to 63.5 and 63.2%, respectively. From these results can be concluded that regarding nutrient composition and utilisation, genetically modified (RR) maize is equivalent to isogenic maize. 相似文献
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Alessio Molinari Anna Lucia Fallacara Salvatore Di Maria Claudio Zamperini Federica Poggialini Francesca Musumeci Silvia Schenone Adriano Angelucci Alessandro Colapietro Emmanuele Crespan Miroslava Kissova Giovanni Maga Maurizio Botta 《Bioorganic & medicinal chemistry letters》2018,28(21):3454-3457
The proto-oncogene c-Src is a non-receptor tyrosine kinase which is involved in the regulation of many cellular processes, such as differentiation, adhesion and survival. c-Src hyperactivation has been detected in many tumors, including neuroblastoma (NB), one of the major causes of death from neoplasia in infancy. We already reported a large family of pyrazolo[3,4-d]pyrimidines active as c-Src inhibitors. Interestingly, some of these derivatives resulted also active on SH-SY5Y NB cell line. Herein, starting from our previous Free Energy Perturbation/Monte Carlo calculations, we report an optimization study which led to the identification of a new series of derivatives endowed with nanomolar Ki values against c-Src, interesting antiproliferative activity on SH-SY5Y cells and a suitable ADME profile. 相似文献
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Summary Studies have been made on the effect of previous cultivation of different plants on soil nitrification. Greater effects were
obtained when the soil was incubated at 29°C and under natural conditions in the open that at 18°C. The rate of nitrification
was usually lower in previously uncultivated than cultivated soils except in the cases of pea, timothy grass and onion when
increased rates were found. 相似文献